Naprosyn 500 Tablet: Uses, Dosage, Side Effects – 2026

Naprosyn 500 is a potent Non-Steroidal Anti-Inflammatory Drug (NSAID) containing Naproxen. It is designed to relieve pain, reduce inflammation, and lower fever by blocking the enzymes (COX-1 and COX-2) that produce prostaglandins. In Bangladesh, Radiant Pharmaceuticals Ltd. produces this high-quality formulation, often preferred for chronic joint and muscle conditions.

What is Naprosyn 500 Used For?

Naprosyn 500 is primarily prescribed for long-lasting relief from:

• Arthritis: Effective for Rheumatoid Arthritis, Osteoarthritis, and Juvenile Arthritis.

• Ankylosing Spondylitis: Relief of stiffness and pain in the spine.

• Acute Gout: Management of sudden, severe joint pain caused by uric acid crystals.

• Musculoskeletal Pain: Treatment of tendonitis, bursitis, sprains, and strains.

• Menstrual Cramps (Dysmenorrhea): Relief of painful period cramps.

• Migraine: Occasionally used for the acute treatment or prevention of migraine headaches.

Clinical studies show that Naproxen has a longer half-life than ibuprofen, providing more sustained relief (up to 12 hours). For more on its efficacy in arthritis, see this clinical review on Naproxen.

Dosage

Naprosyn 500 is typically taken twice daily due to its long-lasting effect.

• For Arthritis/Spondylitis: Usually 500 mg to 1000 mg daily, taken in two divided doses (one in the morning, one in the evening).

• For Acute Gout: A starting dose of 750 mg, followed by 250 mg every 8 hours until the attack subsides.

• For Period Pain: Initially 500 mg, followed by 250 mg every 6 to 8 hours as needed.

• Administration: Must be taken with food or a glass of milk to protect the stomach. Swallow the tablet whole; do not crush or chew.

Key Reminder: Always use the lowest effective dose for the shortest possible duration to minimize the risk of side effects.

Common Side Effects

Naprosyn is generally effective, but like all NSAIDs, it can cause:

• Heartburn or indigestion

• Abdominal pain or nausea

• Headache or dizziness

• Drowsiness

• Swelling (edema) or palpitations

Safety Warning: Long-term use of NSAIDs can increase the risk of serious gastrointestinal bleeding and cardiovascular events (heart attack or stroke). For an updated safety profile, refer to this comprehensive guide on Naproxen side effects.

Important Warnings & Precautions

• Stomach Health: Avoid if you have active stomach ulcers or a history of GI bleeding. Taking it with an antacid (like Sergel or Maxpro) may be recommended by your doctor to protect the stomach.

• Heart/Kidney Disease: Use with extreme caution if you have high blood pressure, heart failure, or kidney impairment.

• Aspirin Allergy: Do not take Naprosyn if you have ever had an asthma attack or allergic reaction to Aspirin or other NSAIDs.

• Alcohol: Avoid alcohol while taking this medicine, as it significantly increases the risk of stomach bleeding.

• Pregnancy: Generally unsafe during pregnancy, particularly in the third trimester, as it can harm the unborn baby.

Price in Bangladesh (January 2026 Approximate)

• Price per Tablet: Approximately ৳16.00.

• Price per Strip (10 Tablets): Typically ৳160.00.

• Manufacturer: Radiant Pharmaceuticals Ltd.

Frequently Asked Questions (FAQ) About Naprosyn 500

Q: Is Naprosyn 500 better than Napa (Paracetamol)?

Naprosyn is stronger for inflammation and lasts longer (12 hours vs. 4-6 hours). However, Napa is safer for the stomach and is usually the first choice for simple fevers or mild headaches.

Q: Can I take Naprosyn 500 on an empty stomach?

No. To avoid severe stomach irritation or ulcers, always take it after a full meal or with milk.

Q: Does it cause sleepiness?

Yes, dizziness and drowsiness are possible side effects. Avoid driving until you know how the medication affects you.

Q: Are there any alternatives to Naprosyn in Bangladesh?

Yes. Popular alternatives include Naprox (Ibn Sina), Naxin (Opsonin), Xenole (Square), Analfex (ACME), and Sonap (Sunman-Global).

Q: What is “Naprosyn Plus”?

Naprosyn Plus is a combination of Naproxen and Esomeprazole. The Esomeprazole helps protect your stomach from the acid irritation caused by the Naproxen.

Disclaimer: This is educational information only (updated January 2026). This is a potent medication that should only be taken under the guidance of a registered physician.