Doxiva 200 is a modern bronchodilator containing Doxophylline. It belongs to the methylxanthine class of drugs, similar to theophylline but with an improved safety profile. It works by relaxing the smooth muscles in the bronchial tubes (airways), making it easier for air to flow in and out of the lungs. In Bangladesh, it is manufactured by NIPRO JMI Pharma Ltd.
What is Doxiva 200 Used For?
Doxiva 200 contains 200 mg of Doxophylline and is primarily prescribed for:
Bronchial Asthma: To prevent and treat wheezing and shortness of breath.
Chronic Obstructive Pulmonary Disease (COPD): Long-term management of chronic bronchitis and emphysema.
Bronchospasm: Relief of sudden constriction of the muscles in the walls of the bronchioles.
Spastic Bronchial Component: Treatment of various pulmonary diseases where the airways become narrowed.
Clinical research indicates that Doxiva selectively inhibits phosphodiesterase 4 (PDE4), providing the same relief as older drugs but with fewer heart-related side effects. For technical details, see this pharmacological review of Doxophylline.
Key Reminder: Doxiva 200 is a maintenance medication. It is not a “rescue” inhaler and should not be used for sudden, severe asthma attacks. Always keep a fast-acting inhaler (like Salbutamol) for emergencies.
Dosage
The dosage for Doxiva 200 depends on the patient’s age and the severity of the condition.
Adults: Usually 400 mg (two 200mg tablets or one 400mg tablet) taken two to three times daily.
Elderly Patients: Often started on 200 mg two or three times daily, as they may process the medication more slowly.
Children (>12 years): One 200 mg tablet taken two to three times daily.
Administration: It is preferably taken in the evening after a meal to help manage nighttime symptoms (nocturnal asthma). Swallow the tablet whole.
Common Side Effects
While Doxiva is generally safer than older xanthines, some users may experience effects similar to having too much caffeine:
Nausea or vomiting
Headache
Upset stomach or heartburn
Irritability or restlessness
Insomnia (difficulty sleeping)
Safety Warning: In rare cases of high dosage, it may cause a fast or irregular heartbeat (tachycardia). If you feel your heart racing, consult your doctor. For an updated safety summary, see this overview on Doxophylline.
Important Warnings & Precautions
Heart Health: Contraindicated in patients with recent acute myocardial infarction (heart attack) or low blood pressure (hypotension).
Smoking: Cigarette smoking can increase how fast your body clears this medicine, meaning smokers might require a higher dose.
Liver/Kidney Disease: Dose adjustments are necessary for patients with liver or kidney impairment.
Pregnancy & Lactation: Should only be used during pregnancy if clearly needed. It is generally contraindicated for nursing mothers.
Drug Interactions: Avoid taking Doxiva with other xanthine derivatives (like Theophylline). It may also interact with Erythromycin, Cimetidine, and the influenza vaccine.
Price in Bangladesh (January 2026 Approximate)
Price per Tablet: Approximately ৳8.00.
Price per Strip (10 Tablets): Typically ৳80.00.
Manufacturer: NIPRO JMI Pharma Ltd.
Frequently Asked Questions (FAQ) About Doxiva 200
Q: Is Doxiva 200 better than Theophylline?
Yes, clinical studies show Doxiva (Doxophylline) has fewer side effects—specifically less impact on the heart and nervous system—than traditional Theophylline.
Q: Can I take Doxiva 200 during the day?
Yes, but many doctors recommend taking it in the evening because asthma and COPD symptoms often worsen at night or early in the morning.
Q: Does Doxiva 200 work immediately?
No. It takes time to build up in your system. It is meant for daily “prevention” rather than “immediate rescue.”
Q: Are there any alternatives to Doxiva in Bangladesh?
Yes. Popular alternatives include Brezofil (Incepta), Docopa (Aristopharma), Fixolin (Beximco), Flindof (Square), and Pulmino (Renata).
Q: Can I drink tea or coffee while taking Doxiva?
Since Doxiva is related to caffeine, drinking large amounts of tea or coffee may increase the risk of jitters, headache, or a racing heart.
Disclaimer: This is educational information only (updated January 2026). Doxiva is a prescription-only drug. Always follow the specific instructions provided by your pulmonologist or general physician
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