Cef-3 is a potent third-generation cephalosporin antibiotic containing Cefixime. It is a bactericidal agent, meaning it kills bacteria by interfering with the synthesis of their cell walls. In Bangladesh, it is a flagship product of Square Pharmaceuticals PLC, highly regarded for its stability against many beta-lactamase enzymes that make other antibiotics (like penicillins) ineffective.
What is Cef-3 Used For?
Cef-3 is prescribed for a wide range of bacterial infections:
Respiratory Tract Infections: Including bronchitis, pneumonia, sinusitis, and tonsillitis.
Urinary Tract Infections (UTIs): Effective for both simple and complicated bladder or kidney infections.
Ear & Throat Infections: Commonly used for acute otitis media (middle ear infection) and pharyngitis.
Typhoid Fever: It is one of the primary oral treatments for enteric fever (typhoid) in the South Asian region.
Gonorrhea: Used as a single-dose treatment for uncomplicated cervical or urethral gonococcal infections.
Clinical research confirms that Cefixime reaches effective concentrations in various body tissues quickly. For more, see this pharmacology study on Cefixime.
Dosage & Forms
Cef-3 comes in various strengths (200mg, 400mg, and pediatric suspensions).
Adults (over 12 years): Usually 200 mg to 400 mg daily, taken either as a single dose or in two divided doses.
Children (6 months to 12 years): Dosage is usually based on weight (8 mg/kg daily).
General guide: 1–4 years: 100 mg daily; 5–10 years: 200 mg daily.
Typhoid Fever: The dose is often higher (10 mg/kg daily) and continued for 14 days.
Administration: Can be taken with or without food. Taking it with a meal may help reduce potential stomach upset.
Key Reminder: Always finish the full course prescribed by your doctor. Stopping early—even if you feel better—can lead to antibiotic resistance.
Common Side Effects
Most patients tolerate Cef-3 well, but common side effects include:
Diarrhea (most common, especially with higher doses)
Nausea or vomiting
Abdominal pain or gas
Headache or dizziness
Skin rash or itching
Safety Warning: If you experience severe, watery, or bloody diarrhea, stop the medication and contact your doctor immediately, as this may be a sign of a secondary bowel infection. For an updated safety profile, refer to this comprehensive review.
Important Warnings & Precautions
Penicillin Allergy: If you are allergic to Penicillin, inform your doctor. There is a risk of “cross-reactivity,” meaning you might also be allergic to Cephalosporins like Cef-3.
Kidney Disease: Patients with severe renal impairment require a dose adjustment.
Alcohol: While no severe direct interaction exists, alcohol can increase dizziness and should be avoided during the course.
Pregnancy & Breastfeeding: Generally considered safe (Category B), but should only be used if clearly needed and prescribed by a doctor.
Anticoagulants: Cef-3 can increase the effect of blood thinners like Warfarin, increasing the risk of bleeding.
Price in Bangladesh (January 2026 Approximate)
Cef-3 200mg Capsule: Approximately ৳45.00 per capsule.
Cef-3 400mg Capsule: Approximately ৳75.00 per capsule.
Cef-3 Powder for Suspension (75ml): Approximately ৳260.00.
Manufacturer: Square Pharmaceuticals PLC.


Frequently Asked Questions (FAQ) About Cef-3
Q: Can I take Cef-3 for a common cold or flu?
No. Cef-3 is an antibiotic for bacteria. It has no effect on viruses like those that cause the cold or flu.
Q: Is Cef-3 safe for infants?
Its safety has not been established for infants under 6 months of age. Always consult a pediatrician for children.
Q: Why is my child’s diarrhea turning orange or changing color?
Changes in stool color and consistency are common side effects of Cefixime and usually resolve once the treatment stops.
Q: Are there any alternatives to Cef-3 in Bangladesh?
Yes. Popular alternatives include Afix (Aristopharma), Denvar (Healthcare), Orcef (Renata), Triocim (Beximco), and Texit (Incepta).
Q: How do I prepare the suspension (syrup)?
Shake the bottle to loosen the powder, then add the exact amount of boiled and cooled water as indicated on the label. Shake well until the powder is fully dissolved. Once mixed, the suspension is usually valid for only 7 to 14 days.
Disclaimer: This is educational information only (updated January 2026). Antibiotics must only be used under the supervision of a registered physician to ensure proper diagnosis and treatment.




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